We investigated how low-methoxyl pectin (LMP) could protect against type 1 diabetes (T1D) using non-obese diabetic mice. The mice were fed a diet with or without 5% LMP for 22 weeks.
Our findings showed that LMP significantly reduced T1D onset and improved gut health. It enhanced the production of beneficial short-chain fatty acids and bolstered gut barrier function. Additionally, LMP fostered a more balanced immune response in the pancreas and gut.
This suggests LMP may serve as a promising supplement for managing T1D.
Read More
9
Pectin diet lessens uveitis severity
A diet rich in fermentable fiber promotes robust changes in the intestinal microbiota, mitigates intestinal permeability, and attenuates autoimmune uveitis.
We investigated how a diet high in pectin, a type of fermentable fiber, affects autoimmune uveitis. In our study using an experimental model, we found that this diet significantly reduced the severity of uveitis by enhancing regulatory T cells while suppressing harmful lymphocytes during peak inflammation. Additionally, a high pectin intake improved intestinal health and permeability, suggesting that dietary changes can play a vital role in managing autoimmune conditions like uveitis.
Read More
9
Low methoxyl pectin limits T1D
Modulation of Gut Microbiota by Low Methoxyl Pectin Attenuates Type 1 Diabetes in Non-obese Diabetic Mice.
We explored how a specific type of low-methoxyl pectin (LMP) can help in preventing type 1 diabetes (T1D) in non-obese diabetic mice. Over 40 weeks, we fed these mice diets either with or without LMP.
The results were promising: mice receiving LMP showed a significant decrease in diabetes symptoms and improved blood glucose levels. The study suggested that LMP promotes a healthier gut microbiota and enhances intestinal barrier functions, which may help in managing T1D.
Overall, our findings provide a potential new avenue for tackling diabetes through dietary changes, which could be relevant for human applications in the future.
Read More
Most Useful Reviews
9
Constipation relief
6 people found this helpful
I was sceptical about the reviews but ordered it due to a year-long battle with constipation, despite dietary adjustments. Surprisingly, after just four to five days, it worked wonders. I take two capsules before meals each morning and afternoon. Now my bathroom visits are stable every day. I'll be reordering!
Read More
9
Supports digestion
5 people found this helpful
Excellent apple pectin! My intestines now operate like clockwork. I ordered two jars at once, as swallowing the capsules is easy. Drinking a large glass of water, preferably before bedtime, is crucial. When taken properly, it aids in bowel movement, nourishes probiotics, and can support weight loss. It has also assisted in addressing acne linked to digestive issues, although for more severe conditions, consulting a doctor remains essential. I recommend this high-quality, affordable product to anyone suffering from constipation!
Read More
9
Improved Hashimoto's
1 people found this helpful
This is a fantastic product for individuals with autoimmune disorders. I recently attended a lecture on how pectin can help improve dysbiosis and regenerate the digestive tract. As a result, I feel significantly better with my Hashimoto's thyroiditis. I'm really enjoying its effects.
A diet rich in fermentable fiber promotes robust changes in the intestinal microbiota, mitigates intestinal permeability, and attenuates autoimmune uveitis.
We investigated how a diet high in pectin, a type of fermentable fiber, affects autoimmune uveitis. In our study using an experimental model, we found that this diet significantly reduced the severity of uveitis by enhancing regulatory T cells while suppressing harmful lymphocytes during peak inflammation. Additionally, a high pectin intake improved intestinal health and permeability, suggesting that dietary changes can play a vital role in managing autoimmune conditions like uveitis.
Read More
9
Pectin impacts autoimmune diabetes positively
Low Methoxyl Pectin Protects against Autoimmune Diabetes and Associated Caecal Dysfunction.
We investigated how low-methoxyl pectin (LMP) could protect against type 1 diabetes (T1D) using non-obese diabetic mice. The mice were fed a diet with or without 5% LMP for 22 weeks.
Our findings showed that LMP significantly reduced T1D onset and improved gut health. It enhanced the production of beneficial short-chain fatty acids and bolstered gut barrier function. Additionally, LMP fostered a more balanced immune response in the pancreas and gut.
This suggests LMP may serve as a promising supplement for managing T1D.
Read More
9
Low methoxyl pectin limits T1D
Modulation of Gut Microbiota by Low Methoxyl Pectin Attenuates Type 1 Diabetes in Non-obese Diabetic Mice.
We explored how a specific type of low-methoxyl pectin (LMP) can help in preventing type 1 diabetes (T1D) in non-obese diabetic mice. Over 40 weeks, we fed these mice diets either with or without LMP.
The results were promising: mice receiving LMP showed a significant decrease in diabetes symptoms and improved blood glucose levels. The study suggested that LMP promotes a healthier gut microbiota and enhances intestinal barrier functions, which may help in managing T1D.
Overall, our findings provide a potential new avenue for tackling diabetes through dietary changes, which could be relevant for human applications in the future.
Read More
8
Pectin-stabilized nanoceria shows promise
Pectin-stabilized nanoceria double coated with lactoferrin/chitosan for management of experimental autoimmune encephalomyelitis.
We examined how pectin-stabilized nanoceria can potentially help in managing autoimmune disorders like multiple sclerosis. This innovative treatment involved creating nanoparticles coated with natural polymers to enhance their delivery to the brain and protect against free radicals.
In our study, both motor function tests and biochemical analyses showed promising outcomes in rats treated over 15 days, including improved motor skills and reduced cellular damage in the brain and spinal cord.
However, while the results were positive, further research is necessary to confirm the long-term benefits and effectiveness of this treatment for autoimmune disorders.
Read More
8
Pectin benefits autoimmune arthritis treatment
Dietary pectin and inulin: A promising adjuvant supplement for collagen-induced arthritis through gut microbiome restoration and CD4 T cell reconstitution.
We explored how a high-fiber diet, especially rich in pectin and inulin, impacts autoimmune conditions like rheumatoid arthritis (RA). In our study, we found that a pectin-rich diet significantly improves outcomes in collagen-induced arthritis in mice.
This effect appears linked to changes in gut bacteria, increasing levels of beneficial butyrate, which help restore the balance of certain immune cells. Our results highlight the potential of dietary changes in managing RA, offering insights into how food can influence immune responses.
I was sceptical about the reviews but ordered it due to a year-long battle with constipation, despite dietary adjustments. Surprisingly, after just four to five days, it worked wonders. I take two capsules before meals each morning and afternoon. Now my bathroom visits are stable every day. I'll be reordering!
Read More
9
Supports digestion
5 people found this helpful
Excellent apple pectin! My intestines now operate like clockwork. I ordered two jars at once, as swallowing the capsules is easy. Drinking a large glass of water, preferably before bedtime, is crucial. When taken properly, it aids in bowel movement, nourishes probiotics, and can support weight loss. It has also assisted in addressing acne linked to digestive issues, although for more severe conditions, consulting a doctor remains essential. I recommend this high-quality, affordable product to anyone suffering from constipation!
Read More
9
Improved Hashimoto's
1 people found this helpful
This is a fantastic product for individuals with autoimmune disorders. I recently attended a lecture on how pectin can help improve dysbiosis and regenerate the digestive tract. As a result, I feel significantly better with my Hashimoto's thyroiditis. I'm really enjoying its effects.
Read More
9
Kid-friendly
1 people found this helpful
This is a superb product for both my daughter with constipation and myself. After two years of struggling, she finally has regular bowel movements. I frequently drink it in the morning and will definitely order more.
Read More
9
Constipation remedy
18 people found this helpful
I have only been taking this supplement for a week, but the results are already noticeable! My digestive system works seamlessly now. It’s gentle in alleviating constipation and has a very good composition. I’ve ordered another jar due to the excellent cleansing effects, and I've found it works particularly well in conjunction with probiotics. If you find this review helpful, please give it a like!
An autoimmune disorder occurs when the body's immune system mistakenly attacks its own healthy cells and tissues, believing them to be foreign invaders, such as bacteria or viruses. This reaction can lead to inflammation, tissue damage, and impaired function of the affected organs. There are over 80 known autoimmune diseases, including rheumatoid arthritis, lupus, multiple sclerosis, and type 1 diabetes, each with its own specific symptoms and treatment options. The exact cause of these disorders is still unclear, but a combination of genetic, environmental, and hormonal factors is believed to play a role in their development.
Diagnosis of autoimmune disorders often involves a combination of physical examinations, assessment of symptoms, blood tests, and imaging studies to evaluate organ involvement. Treatment typically focuses on managing symptoms and controlling the immune response using medications such as corticosteroids, immunosuppressants, and biologics. In addition to medication, lifestyle modifications, such as stress management and a balanced diet, can be beneficial in managing symptoms. If you suspect you have an autoimmune condition, it's important to consult a healthcare professional for proper evaluation and tailored treatment options.
Pectin is a naturally occurring polysaccharide found in the cell walls of fruits and vegetables, playing a crucial role in their structure and texture. Primarily used as a gelling agent in food preservation, pectin is famous for its ability to form gels when combined with sugar and acid. This makes it an essential ingredient in jams, jellies, and fruit preserves, helping them achieve that desirable thick consistency that many home cooks strive for.
In addition to its culinary uses, pectin is also recognized for its health benefits. It can act as a soluble fiber, potentially aiding in digestive health and helping to regulate blood sugar levels and cholesterol. For those interested in cooking or baking, understanding pectin’s properties can elevate your recipes, allowing you to create a variety of thickened sauces and spreads with the perfect texture. If you’re looking to experiment with pectin in your kitchen, you’ll find it sold in powder or liquid form in grocery stores, often located in the baking aisle.
Based on user reviews, the time it takes to see results from apple pectin supplementation for autoimmune disorders can vary. Many users have reported noticeable improvements within a relatively short period. For instance, one reviewer shared that they felt significantly better after just a week of use, indicating a positive effect on their well-being related to Hashimoto's thyroiditis Read Review. Another user mentioned experiencing improvements in intestinal motility and overall health shortly after starting the supplement Read Review.
While some users have experienced results within days, others have pointed out that outcomes can depend on individual circumstances and might not work uniformly for all individuals with autoimmune conditions. For example, a reviewer stated that the supplement wasn't effective for their mother Read Review. Therefore, while many users report quick results, it is important to consider personal health conditions when assessing the supplement's impact.
The scientific research supports the idea that pectin may play a beneficial role in the management of various autoimmune disorders. Studies have shown that a pectin-rich diet can significantly improve outcomes for conditions such as rheumatoid arthritis, systemic lupus erythematosus, and autoimmune uveitis. For example, a study indicated that mice on a pectin-rich diet exhibited enhanced regulatory T cell activity, which is crucial for moderating immune responses and reducing inflammation in autoimmune conditions like uveitis [4]. Additionally, research exploring the use of low-methoxyl pectin (LMP) in type 1 diabetes demonstrated that it may reduce diabetes onset and promote better gut health, suggesting a potential avenue for dietary intervention in managing this autoimmune disorder [5].
Furthermore, innovative drug delivery systems using pectin have shown promise in improving the absorption and effectiveness of medications for systemic lupus erythematosus, highlighting pectin's potential not just as a dietary supplement, but also as a component in therapeutic formulations [3]. While these findings are encouraging, it is important to note that further research is necessary to validate these results and explore long-term effects in humans. As such, while current data points to the potential benefits of pectin for autoimmune disorders, additional studies will solidify its standing in clinical practice.
Users have reported a range of improvements in symptoms associated with digestive health and autoimmune disorders after incorporating apple pectin into their routines. Many individuals have experienced significant relief from constipation within just a few days of starting the supplement. For instance, one user noted that after a long struggle with constipation, apple pectin helped establish regular bowel movements just four to five days after starting the capsules Read Review. Another reviewer echoed similar sentiments, stating their intestines now operate smoothly and they are relieved of bloating and discomfort Read Review.
Moreover, users dealing with autoimmune conditions have found benefits as well. One reviewer shared that they felt markedly better as a result of addressing dysbiosis related to their Hashimoto's thyroiditis Read Review. Similarly, several comments indicated improvements in overall well-being and digestive function when used alongside other supplements Read Review. However, it is essential to note that experiences differ widely; some users reported minimal or no effect on their symptoms, particularly those with more severe autoimmune disorders Read Review. As with any supplement, individual results can vary significantly.
Users have reported mixed experiences when combining apple pectin with other supplements for managing autoimmune disorders. Some individuals found that combining apple pectin with probiotics and other digestive aids enhanced its effectiveness. For instance, one reviewer noted significant improvements in digestion after taking apple pectin alongside inulin and super enzymes, indicating a synergistic effect that alleviated intestinal rumbling Read Review. Additionally, another user mentioned feeling markedly better while using apple pectin for Hashimoto's thyroiditis, suggesting that it may help address underlying digestive issues associated with autoimmune conditions Read Review.
However, not all users experienced positive outcomes. Some shared that despite combining apple pectin with other products, they did not see improvements in their autoimmune symptoms. One reviewer highlighted the mildness of the supplement for their mother's condition, indicating that it may not work uniformly across different individuals Read Review. Similarly, another individual mentioned that while the product did not suit their needs, they did pair it with another supplement Read Review. Thus, while many users report beneficial interactions, results can vary widely based on individual circumstances and health status.
Users have shared varied experiences regarding the right dosage of pectin for treating autoimmune disorders. Many have found success with dosages of two capsules taken on an empty stomach, typically with a glass of water half an hour before meals. For instance, one reviewer reported notable improvements in their overall well-being and intestinal motility while using this dosage to manage their autoimmune condition Read Review. Another user confirmed similar positive effects after incorporating pectin into their routine, stating it contributed significantly to their health alongside other dietary practices Read Review.
However, it's worth noting that not all users experienced the same benefits. One reviewer mentioned the product wasn't as effective for their autoimmune disorder, indicating that individual reactions can vary widely Read Review. The general consensus among users seems to advocate for a dosage of around two capsules, though it’s essential for individuals with specific health issues to consult with their healthcare providers to determine the best approach for their circumstances.
9
Improved Hashimoto's
1 people found this helpful
This is a fantastic product for individuals with autoimmune disorders. I recently attended a lecture on how pectin can help improve dysbiosis and regenerate the digestive tract. As a result, I feel significantly better with my Hashimoto's thyroiditis. I'm really enjoying its effects.
7.5
Improved motility
3 people found this helpful
After starting the pectin, my intestinal motility and overall well-being improved. I took 2 capsules on an empty stomach with a glass of water half an hour before meals. I intend to order more as it has positively affected my autoimmune disorder.
2
Limited effectiveness
I ordered it for my mother, who is over 80, yet it did not prove very helpful in addressing her autoimmune disorder.
9
Constipation relief
6 people found this helpful
I was sceptical about the reviews but ordered it due to a year-long battle with constipation, despite dietary adjustments. Surprisingly, after just four to five days, it worked wonders. I take two capsules before meals each morning and afternoon. Now my bathroom visits are stable every day. I'll be reordering!
9
Supports digestion
5 people found this helpful
Excellent apple pectin! My intestines now operate like clockwork. I ordered two jars at once, as swallowing the capsules is easy. Drinking a large glass of water, preferably before bedtime, is crucial. When taken properly, it aids in bowel movement, nourishes probiotics, and can support weight loss. It has also assisted in addressing acne linked to digestive issues, although for more severe conditions, consulting a doctor remains essential. I recommend this high-quality, affordable product to anyone suffering from constipation!
7.5
Improved digestion
3 people found this helpful
I tried it for the first time, and I really liked the effect. However, I should mention that I took it alongside inulin, super enzymes from the same manufacturer, and LactoBif Probiotics. After two weeks of use, my digestion improved, and the rumbling in my intestines ceased. I've ordered two more cans.
2
Aids digestion
17 people found this helpful
It works well for me. I took it alongside parasite treatment for effective purification. Occasionally, I utilised it after meals to aid digestion, which greatly helped. I reordered, but it didn't help my mother as she found it too mild for her autoimmune disorder.
4
Not effective
It doesn't seem to suit me. The product wasn't very effective for my autoimmune disorder, but I paired it with a different product.
9
Pectin diet lessens uveitis severity
A diet rich in fermentable fiber promotes robust changes in the intestinal microbiota, mitigates intestinal permeability, and attenuates autoimmune uveitis.
We investigated how a diet high in pectin, a type of fermentable fiber, affects autoimmune uveitis. In our study using an experimental model, we found that this diet significantly reduced the severity of uveitis by enhancing regulatory T cells while suppressing harmful lymphocytes during peak inflammation. Additionally, a high pectin intake improved intestinal health and permeability, suggesting that dietary changes can play a vital role in managing autoimmune conditions like uveitis.
9
Pectin impacts autoimmune diabetes positively
Low Methoxyl Pectin Protects against Autoimmune Diabetes and Associated Caecal Dysfunction.
We investigated how low-methoxyl pectin (LMP) could protect against type 1 diabetes (T1D) using non-obese diabetic mice. The mice were fed a diet with or without 5% LMP for 22 weeks.
Our findings showed that LMP significantly reduced T1D onset and improved gut health. It enhanced the production of beneficial short-chain fatty acids and bolstered gut barrier function. Additionally, LMP fostered a more balanced immune response in the pancreas and gut.
This suggests LMP may serve as a promising supplement for managing T1D.
8
Pectin-based delivery system effective
Exploring pectin-casein micelles as novel carriers for oral drug delivery of artesunate in the treatment of systemic lupus erythematosus.
We explored an innovative delivery system utilizing pectin and casein micelles to improve the oral administration of artesunate for treating systemic lupus erythematosus (SLE). By creating these micelles, we addressed common issues associated with oral medication, such as stability and absorption.
The results showed enhanced drug loading, stability, and bioavailability, which contributed to the alleviation of SLE symptoms in tested mice. Overall, this approach offers promising potential for effective long-term oral treatment of chronic autoimmune disorders.
References
Abdelalim LR, Elnaggar YSR, Abdallah OY. Pectin-stabilized nanoceria double coated with lactoferrin/chitosan for management of experimental autoimmune encephalomyelitis. Colloids Surf B Biointerfaces. 2025;245:114271. doi:10.1016/j.colsurfb.2024.114271
Lou Y, Wen X, Song S, Zeng Y, Huang L, et al. Dietary pectin and inulin: A promising adjuvant supplement for collagen-induced arthritis through gut microbiome restoration and CD4 T cell reconstitution. J Nutr Biochem. 2024;133:109699. doi:10.1016/j.jnutbio.2024.109699
Zhang Y, Meng Y, Wang S, Zu Y, Zhao X. Exploring pectin-casein micelles as novel carriers for oral drug delivery of artesunate in the treatment of systemic lupus erythematosus. Int J Biol Macromol. 2024;271:132523. doi:10.1016/j.ijbiomac.2024.132523
Nakamura YK, Metea C, Llorenç V, Karstens L, Balter A, et al. A diet rich in fermentable fiber promotes robust changes in the intestinal microbiota, mitigates intestinal permeability, and attenuates autoimmune uveitis. Sci Rep. 2023;13:10806. doi:10.1038/s41598-023-37062-8
Wu C, Pan LL, Luo Y, Niu W, Fang X, et al. Low Methoxyl Pectin Protects against Autoimmune Diabetes and Associated Caecal Dysfunction. Mol Nutr Food Res. 2019;63:e1900307. doi:10.1002/mnfr.201900307
Wu C, Pan LL, Niu W, Fang X, Liang W, et al. Modulation of Gut Microbiota by Low Methoxyl Pectin Attenuates Type 1 Diabetes in Non-obese Diabetic Mice. Front Immunol. 2019;10:1733. doi:10.3389/fimmu.2019.01733
Ramasamy T, Ruttala HB, Shanmugam S, Umadevi SK. Eudragit-coated aceclofenac-loaded pectin microspheres in chronopharmacological treatment of rheumatoid arthritis. Drug Deliv. 2013;20:65. doi:10.3109/10717544.2012.762434
Corrocher G, Di Lorenzo G, Mansueto P, Martinelli N, Esposito-Pellitteri M, et al. Comparison of topical tacrolimus 0.1 % in pectin ointment with clobetasol 0.5% ointment in adults with moderate to severe desquamative gingivitis: A 4-week, randomized, double-blind clinical trial. Clin Ther. 2006;28:1296.